Friday, March 28, 2008
Relative efficacy and side effects of Helminthic Therapy
The potential benefits of Helminthic Therapy are even more startling when taken in the context of the success rates and side-effects experienced by people on currently accepted medications that are immune-modulating and or anti-inflammatory. Success rates for helminthic therapy, as measured by the number of people achieving remission range from 56% for Ulcerative Colitis using TSO as the helminth, 72% for Crohn's using TS, and 100% for Crohn's disease using hookworm. Contrast that with the remission rates for the new biologicals as described below, in one study sponsored by the drug maker, Humira achieved only a 52% remission rate in Crohn's patients. As well, side effects of helminthic therapies are not universal and are temporary, usually lasting only two to four weeks. They consist of abdominal pain, cramping, gas, diarrhea and fatigue. The side effects of conventional immune-modulating drugs, such as Beta-interferon and Remicade, or of anti-inflammatories such prednisone, are much more severe and potentially harmful. As with any immunosuppressive therapies patients using helminthic therapy are likely to be more susceptible to certain infectious diseases.
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